| Town Name | Type | Region | Province / State | County | Municipality | Population | Latitude | Longitude | |
|---|---|---|---|---|---|---|---|---|---|
| Sallisaw | town | South | Oklahoma | Sequoyah | 8510 | 35.458733 | -94.787941 | Map | |
| Salmon | town | West | Idaho | Lemhi | 3059 | 45.175755 | -113.895905 | Map | |
| Salt Lake City | city | West | Utah | Salt Lake | 199723 | 40.759621 | -111.886795 | Map | |
| Saltillo | town | South | Mississippi | Lee | 4922 | 34.376591 | -88.684464 | Map | |
| Salton City | village | West | California | Imperial | 4784 | 33.298649 | -115.956108 | Map | |
| Sammamish | town | West | Washington | King | 67455 | 47.608845 | -122.042305 | Map | |
| Samsula-Spruce Creek | village | South | Florida | Volusia | 5047 | 29.052996 | -81.062202 | Map | |
| San Angelo | city | South | Texas | Tom Green | 99893 | 31.464970 | -100.440506 | Map | |
| San Anselmo | town | West | California | Marin | 12043 | 37.974434 | -122.561501 | Map | |
| San Antonio | city | South | Texas | Bexar | 1434625 | 29.424601 | -98.495140 | Map | |
| San Benito | town | South | Texas | Cameron | 25005 | 26.132624 | -97.630791 | Map | |
| San Bernardino | city | West | California | San Bernardino | 198985 | 34.108345 | -117.289764 | Map | |
| San Bruno | town | West | California | San Mateo | 41114 | 37.626171 | -122.433243 | Map | |
| San Carlos | town | West | California | San Mateo | 27002 | 37.504936 | -122.261826 | Map | |
| San Clemente | city | West | California | Orange | 65526 | 33.427029 | -117.612419 | Map | |
| San Diego | town | South | Texas | Duval | 4488 | 27.763914 | -98.238892 | Map | |
| San Diego | city | West | California | San Diego | 1386932 | 32.717419 | -117.162773 | Map | |
| San Dimas | town | West | California | Los Angeles | 35714 | 34.106674 | -117.806725 | Map | |
| San Elizario | town | South | Texas | El Paso | 10116 | 31.586983 | -106.266014 | Map | |
| San Fernando | town | West | California | Los Angeles | 24119 | 34.284969 | -118.437653 | Map | |
| San Francisco | city | West | California | San Francisco | 873965 | 37.779026 | -122.419907 | Map | |
| San Gabriel | town | West | California | Los Angeles | 39718 | 34.099072 | -118.108566 | Map | |
| San Jacinto | town | West | California | Riverside | 48867 | 33.783966 | -116.958908 | Map | |
| San Joaquin | village | West | California | Fresno | 4001 | 36.606617 | -120.189049 | Map | |
| San Jose | city | West | California | Santa Clara | 1013240 | 37.336166 | -121.890594 | Map |
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